Electroporation enhances protective immune response of a DNA vaccine against Japanese encephalitis in mice and pigs

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial

Cornelia L. Trimble, Matthew P. Morrow, Kimberly A. Kraynyak et al. · The Lancet · 2015 · 714 citations

Medicine, Immunology, Oncology +17

The Anamnestic Neutralizing Antibody Response Is Critical for Protection of Mice from Challenge following Vaccination with a Plasmid Encoding the Japanese Encephalitis Virus Premembrane and Envelope Genes

Eiji Konishi, Masaoki Yamaoka, Khin-Sane-Win et al. · Journal of Virology · 1999 · 122 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +15

Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C

Ola Weiland, Gustaf Ahlén, Helmut M. Diepolder et al. · Molecular Therapy · 2013 · 77 citations · Full text

Pharmacy, Immunology, Infectious Diseases +17

A Phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for haemorrhagic fever with renal syndrome delivered by intramuscular electroporation

Jay W. Hooper, James E. Moon, Kristopher Paolino et al. · Clinical Microbiology and Infection · 2014 · 76 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

Juliet Mpendo, Gaudensia Mutua, Julien Nyombayire et al. · PLoS ONE · 2015 · 44 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17