Dalton Transactions · 2016 · 48 citations · 34 references
PharmacyOncologyPharmacologyCancer PharmacologyDrug DeliveryNanoparticle Drug DeliveryCancer NanomedicineCancer Stem CellsDrug EncapsulationNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineBiocompatible Polymeric NanoparticlesBiodegradable Polymeric NanoparticlesInorganic Nanoparticle FormulationNanoparticle Toxicity ReductionNanoparticle-based ChemotherapyPolymeric Nanoparticle FormulationReactive Oxygen Species-responsive NanoparticlesThree-dimensional Cell Culture
selectively kills breast CSCs over bulk breast cancer cells, and evokes a similar cellular response to the payload, 3c. To the best of our knowledge, this is the first study to demonstrate that polymeric nanoparticles can be used to effectively deliver CSC-potent metal complexes into CSCs.
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Prospective identification of tumorigenic breast cancer cells
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