Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

Abstract

Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.