Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

Abstract

In conclusion, PCDH1 is localized to the cell membrane of bronchial epithelial cells baso-lateral to the adherens junction. Expression of PCDH1 is not reduced nor delocalized in asthma even though PCDH1 contributes to homotypic adhesion, epithelial barrier formation and repair.