Arene ruthenium(<scp>ii</scp>) complexes with chalcone, aminoantipyrine and aminopyrimidine based ligands: synthesis, structure and preliminary evaluation of anti-leukemia activity

Abstract

A series of arene ruthenium(<sc>ii</sc>) complexes with<italic>N</italic>-monodentate (AAP) and<italic>N</italic>,<italic>O</italic>- and<italic>N</italic>,<italic>N</italic>-bidentate chelating ligands (AAPS, ADABS, AAPPA and P2P) have been synthesized and evaluated for preliminary antileukemia activity against K562 (Human chronic myeloid leukemia cell line).