Inhibition of Aurora A Kinase by Alisertib Induces Autophagy and Cell Cycle Arrest and Increases Chemosensitivity in Human Hepatocellular Carcinoma HepG2 Cells - Concepedia

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Inhibition of Aurora A Kinase by Alisertib Induces Autophagy and Cell Cycle Arrest and Increases Chemosensitivity in Human Hepatocellular Carcinoma HepG2 Cells

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References

2016

Year

Qiaohua Zhu, Xinfa Yu, Zhi-Wei Zhou, Chengyu Zhou, Xiao-Wu Chen, Shu-Feng Zhou

Current Cancer Drug Targets

Abstract

Background: Aurora A kinase represent a feasible target in cancer therapy. Keywords: Hepatocellular carcinoma, HepG2 cells, aurora kinase A, alisertib, cell cycle, programmed cell death, SILAC, proteomics.