A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme

Abstract

A PHASE III RANDOMIZED CONTROLLED TRIAL OF SHORT-COURSE RADIOTHERAPY WITH OR WITHOUT CONCOMITANT AND ADJUVANT TEMOZOLOMIDE IN ELDERLY PATIENTS WITH GLIOBLASTOMA (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677) James R. Perry MD, FRCPC, Christopher J. O’Callaghan, Keyue Ding, Wilson Roa, Warren P. Mason, J. Gregory Cairncross, Alba Ariela Brandes, Johan Menten, Claire Phillips, Michael F. Fay, Ryo Nishikawa, Chad Winch, and Normand Laperriere; University of Toronto, Odette Cancer Centre