Culture-Negative Severe Sepsis

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.8K citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +15

Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases

Richard A. Deyo · Journal of Clinical Epidemiology · 1992 · 10.5K citations

Education, Health Informatics, Clinical Classification Systems +12

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

Anand Kumar, Daniel Roberts, Kenneth E. Wood et al. · Critical Care Medicine · 2006 · 6.1K citations

Veterinary Medicine, Infectious Diseases, Antimicrobial Pharmacotherapy +13

The Epidemiology of Sepsis in the United States from 1979 through 2000

Greg S. Martin, David M. Mannino, Stephanie Eaton et al. · New England Journal of Medicine · 2003 · 5.9K citations · Full text

Veterinary Medicine, Demography, Infectious Diseases +17

Sepsis in European intensive care units: Results of the SOAP study*

Jean‐Louis Vincent, Yasser Sakr, Charles L. Sprung et al. · Critical Care Medicine · 2006 · 2.9K citations

Veterinary Medicine, Infectious Diseases, Microbiology +14