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Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A 2 group IIA, 5-lipoxygenase and cyclooxygenase-2

InflammationAnti-inflammatorySignal TransductionOxysterolBiochemistryGroup IiaMedicineLipid PeroxidationArachidonic Acid PathwayCatalytic ActivityReactive Oxygen SpeciePharmacologyCell BiologyCell SignalingLipid SynthesisOxidative Stress