Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation - Concepedia

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Publication | Open Access

Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation

DOI Full Paper Access

40

Citations

43

References

2016

Year

Mandar Bawadekar, Annette Gendron‐Fitzpatrick, Ryan J. Rebernick, Daeun Shim, Thomas F. Warner, Anthony P. Nicholas, Lennart K. A. Lundblad, Paul R. Thompson, Miriam A. Shelef

Arthritis Research & Therapy

Abstract

PAD4 exacerbates lung inflammation downstream of TNF-α without having a major role in generalized protein citrullination in inflamed lungs. Also, TNF-α-induced lung inflammation is not sufficient to drive murine arthritis.

References

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