Concepedia

Bone marrow stem cells and their niche components are adversely affected in advanced cirrhosis of the liver

Chhagan Bihari, Lovkesh Anand, Sheetalnath Rooge, Dhananjay Kumar, Priyanka Saxena, Smriti Shubham, Sukriti Sukriti, Nirupma Trehanpati, Guresh Kumar, Viniyendra Pamecha,

Hepatology · 2016 · 64 citations · 34 references

DOI

Abstract

Increasing severity of cirrhosis causes derangement of the hematopoietic niche and loss of HSCs, contributing to the hematological and immunological dysfunctions and reduced potential for regeneration; restoring BM functions could provide new therapeutic options in cirrhosis. (Hepatology 2016;64:1273-1288).

References

34

Revising consensus in portal hypertension: Report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension

Roberto de Franchis · Journal of Hepatology · 2010 · 2.3K citations · Full text

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

Anne Wilson, Elisa Laurenti, Gabriela Oser et al. · Cell · 2008 · 1.8K citations

, , +6

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

Bo Zhou, Rui Yue, Malea M. Murphy et al. · Cell stem cell · 2014 · 1.4K citations · Full text

, , +11

Evolving Consensus in Portal Hypertension Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension

Roberto de Franchis · Journal of Hepatology · 2005 · 1K citations

, , +8

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

Megan T. Baldridge, Katherine Y. King, Nathan C. Boles et al. · Nature · 2010 · 854 citations · Full text

, , +11