A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason et al. · The Lancet Oncology · 2009 · 7.8K citations

Medicine, Oncology, Radiation Oncology +17

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.7K citations · Full text

Medicine, Molecular Genetics, Oncology +12

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

Medicine, Cancer Biology, Oncology +16

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Heidi Phillips, Samir Kharbanda, Ruihuan Chen et al. · Cancer Cell · 2006 · 3.2K citations · Full text

Medicine, Neuroscience, Oncology +16

A restricted cell population propagates glioblastoma growth after chemotherapy

Jian Chen, Yanjiao Li, Tzong‐Shiue Yu et al. · Nature · 2012 · 2.3K citations

Medicine, Cancer Biology, Oncology +14