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Publication | Open Access

Liposomal Treatment of Experimental Arthritis Can Be Monitored Noninvasively with a Radiolabeled Anti–Fibroblast Activation Protein Antibody

DOIFull Paper Access

38

Citations

12

References

2016

Year

Tessa van der Geest, Peter Laverman, Danny Gerrits, Birgitte Walgreen, Monique M. Helsen, Christian Klein, Tapan K. Nayak, Gert Storm, Josbert M. Metselaar, Marije I. Koenders,
Journal of Nuclear Medicine

Abstract

SPECT/CT imaging with <sup>99m</sup>Tc-S-HYNIC-28H1 specifically monitored the response to therapy, and tracer accumulation correlated with the severity of inflammation. In addition, SPECT/CT imaging was potentially more sensitive than the macroscopic arthritis scoring method. This study showed that SPECT/CT with <sup>99m</sup>Tc-S-HYNIC-28H1 could be used to noninvasively monitor the course of CIA in mice.

References

YearCitations

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