Synthesis of Some New Heterocycles Derived from Ethyl 7‐Amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5<i>H</i>‐thiazolo[3,2‐<i>a</i>]pyrimidine‐6‐carboxylate of Biological Importance

Mohamed Salah K. Youssef, Mohamed S. Abbady, Ragaa A. Ahmed, Ahmed A. Omar

Journal of Heterocyclic Chemistry · 2013 · 12 citations · 9 references

Concepts

Abstract

Ethyl 7‐amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate was synthesized by the reaction of 4‐(2‐aminothiazol‐4‐yl)‐3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems via reaction with various reagents. The biological activities of these compounds were evaluated.

References

9