Journal of Heterocyclic Chemistry · 2013 · 12 citations · 9 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsActivitiesAmino Acid-derived HeterocyclesBioactive HeterocyclesFused Heterocyclic SystemsMedicinal HeterocyclesPyrimidine ChemistryThiazole ChemistryThiazole Synthesis
Ethyl 7‐amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate was synthesized by the reaction of 4‐(2‐aminothiazol‐4‐yl)‐3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems via reaction with various reagents. The biological activities of these compounds were evaluated.
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5H-thiazolo[3,2-a]pyrimidine derivatives as a new type of acetylcholinesterase inhibitors
Hui Zhi, Lanmei Chen, Linlin Zhang et al. · ARKIVOC · 2008 · 76 citations · Full text
Chandrahas N. Khobragade, Ragini G. Bodade, Bhaskar S. Dawane et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2009 · 24 citations