Secreted amyloid precursor protein-alpha can restore novel object location memory and hippocampal LTP in aged rats

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

A. Ennaceur, Jean Delacour · Behavioural Brain Research · 1988 · 3.2K citations

Social Sciences, Neurobiology, Neuroscience +16

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

Carol A. Barnes · Journal of Comparative and Physiological Psychology · 1979 · 2.1K citations

Life Sciences, Neurobiology, Neuroscience +17

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Saul Villeda, Jian Luo, Kira I. Mosher et al. · Nature · 2011 · 1.8K citations · Full text

Education, Neurobiology, Neuroscience +14

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

Mark P. Mattson, Bin Cheng, Alan R. Culwell et al. · Neuron · 1993 · 799 citations

Life Sciences, Neurobiology, Neuroscience +16

Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation <i>in vitro</i> and are attenuated by drugs that enhance the cAMP signaling pathway

Mary Elizabeth Bach, Mark Barad, Hyeon Son et al. · Proceedings of the National Academy of Sciences · 1999 · 567 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17