Pharmacokinetics of ketamine and three metabolites in Beagle dogs under sevoflurane vs. medetomidine comedication assessed by enantioselective capillary electrophoresis

Ketamine Pharmacology: An Update (<i>Pharmacodynamics and Molecular Aspects, Recent Findings</i>)

G. Mion, Thierry Villevieille · CNS Neuroscience & Therapeutics · 2013 · 686 citations · Full text

Medicine, Pharmacology, Anesthesia +14

Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs

Kuusela, Marja Raekallio, Anttila et al. · Journal of Veterinary Pharmacology and Therapeutics · 2000 · 298 citations

Medicine, Pharmacokinetics, Pharmacology +13

Contribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms to N-Demethylation of Ketamine in Human Liver Microsomes

Youssef Hijazi, Roselyne Boulieu · Drug Metabolism and Disposition · 2002 · 285 citations

Medicine, Biochemistry, Pharmacology +14

Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression

Carlos A. Zarate, Nancy E. Brutsché, Gonzalo Laje et al. · Biological Psychiatry · 2012 · 283 citations · Full text

Medicine, Pharmacology, Psychiatry +16

Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes.

Yoshitsugu Yanagihara, Satoru Kariya, Michiteru Ohtani et al. · PubMed · 2001 · 190 citations

Medicine, Biochemistry, Pharmacology +17