PubMed · 2016 · 15 citations · 25 references
Open access
Life SciencesNeurobiologyNeuroscienceMemoryNeurobiology Of DiseaseParasitologyNeurological Parasitic DiseasesParasitic Disease PathogenesisParasitic DiseasesParasitic PathogenesisRodent Infectious DiseasesRodent ParasitologyAcetylcholinesterase FunctionAcetylcholinesterase InhibitorsAche InhibitionAlzheimer's Disease ModelsAnimal Model PharmacologySpatial Short-term MemoryToxoplasmosis In RodentsToxoplasmosis Treatment
BACKGROUND: infection. METHODS: <0.05 was considered statistically significant. RESULTS: infection. CONCLUSION: infection through increasing AChE reduces the level of Acetylcholine (Ach) and consequently affects learning and memory activity in infected hosts, whereas, donepezil as an AChE inhibitor improves these impairments by restoring ACh levels at synapses of neurons in brain.
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The Neurotropic Parasite Toxoplasma Gondii Increases Dopamine Metabolism
Emese Prandovszky, Elizabeth A. Gaskell, Heather L. Martin et al. · PLoS ONE · 2011 · 457 citations · Full text
Toxoplasma gondii Actively Inhibits Neuronal Function in Chronically Infected Mice
Fahad Haroon, Ulrike Händel, Frank Angenstein et al. · PLoS ONE · 2012 · 104 citations · Full text