Effect of Uridine on the Metabolism of 5-Fluorouracil in the CD8F1 Murine Mammary Carcinoma System

Effect of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil.

Setsuro Fujii, Kazuhiro Ikenaka, Masakazu Fukushima et al. · PubMed · 1978 · 185 citations

Medicine, Oncology, Pharmacology +10

Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas

T.H. Corbett, Daniel P. Griswold, Bill J. Roberts et al. · Cancer · 1977 · 182 citations

Medicine, Oncology, Pharmacology +9

Effect of coadministration of uracil or cytosine on the anti-tumor activity of clinical doses of 1-(2-tetrahydrofuryl)-5-fluorouracil and level of 5-fluorouracil in rodents.

Setsuro Fujii, Shizuo Kitano, Kazuhiro Ikenaka et al. · PubMed · 1979 · 172 citations

Medicine, Oncology, Pharmacology +17

Effect of uracil on metabolism of 5-fluorouracil in vitro.

Kazuhiro Ikenaka, Tetshuhiko Shirasaka, Shizuo Kitano et al. · PubMed · 1979 · 142 citations

Life Sciences, Biochemistry, Pharmacology +9

Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.

Charles E. Myers, Robert C. Young, Bruce A. Chabner · Journal of Clinical Investigation · 1975 · 119 citations · Full text

Medicine, Biochemistry, Pharmacology +17