Concepedia

Assessing Analytical Similarity of Proposed Amgen Biosimilar ABP 501 to Adalimumab

Jennifer Liu, Tamer Eris, Cynthia Li, Shawn Cao, Scott Kuhns

BioDrugs · 2016 · 97 citations · 25 references

DOIFull text

Open access

Abstract

Based on the comprehensive analytical similarity assessment, ABP 501 was found to be similar to adalimumab with respect to physicochemical and biological properties.

References

25

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

Peter Schuck · Biophysical Journal · 2000 · 3.9K citations · Full text

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Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity

Robert L. Shields, Jadine Lai, Rodney G. Keck et al. · Journal of Biological Chemistry · 2002 · 1.8K citations · Full text

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The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

WHO Expert Committee on Biological Standardization.

Blanche Horowitz, P. Minor, Morgenthaler Jj et al. · PubMed · 1994 · 541 citations

High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans

Andrew M. Goetze, Diana Liu, Zhongqi Zhang et al. · Glycobiology · 2011 · 458 citations