Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis

Randomized Phase III Trial of Marimastat Versus Placebo in Patients With Metastatic Breast Cancer Who Have Responding or Stable Disease After First-Line Chemotherapy: Eastern Cooperative Oncology Group Trial E2196

Joseph A. Sparano, Patricia Bernardo, Patricia Stephenson et al. · Journal of Clinical Oncology · 2004 · 268 citations · Full text

Medicine, Oncology, Pharmacology +17

Catalytic Activity of ADAM8, ADAM15, and MDC-L (ADAM28) on Synthetic Peptide Substrates and in Ectodomain Cleavage of CD23

Anne M. Fourie, Fawn Coles, Veronica Moreno et al. · Journal of Biological Chemistry · 2003 · 184 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The Metalloprotease Disintegrin ADAM8

Uwe Schlomann, Dirk Wildeboer, Ailsa Webster et al. · Journal of Biological Chemistry · 2002 · 169 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

ADAM8 as a Novel Serological and Histochemical Marker for Lung Cancer

Nobuhisa Ishikawa, Yataro Daigo, Wataru Yasui et al. · Clinical Cancer Research · 2004 · 149 citations · Full text

Medicine, Oncology, Pathology +17

Metalloproteinase Disintegrins ADAM8 and ADAM19 Are Highly Regulated in Human Primary Brain Tumors and their Expression Levels and Activities Are Associated with Invasiveness

Dirk Wildeboer, Silvia Naus, Qing‐Xiang Amy Sang et al. · Journal of Neuropathology & Experimental Neurology · 2006 · 145 citations · Full text

Medicine, Molecular Biology, Oncology +17