Wound Healing Profiles of Ginkgo biloba

Abstract

Objective: To evaluate the effects of Ginkgo biloba on wound healing. Materials and methods: The wound healing effects of dried extract of Ginkgo Biloba (GB) were tested at a dose of 50 mg/kg on dead space and excision wound models in male rats. Results: GB has significantly (p< 0.01) promoted the breaking strength and hydroxyproline content of granulation tissue in dead space wounds. In case of excision wounds while it did not affect the wound contraction, the epithelization period was significantly (p<0.01) shortened. Conclusion: GB exhibits a significant pro-healing activity, possibly by influencing the collagenation phase of wound healing.