The occurrence of bacteremia and death in cortisone treated mice.

Abstract

Abstract Cortisone was administered subcutaneously to laboratory mice with the following results: (1) Animals treated with large doses of cortisone died and at autopsy showed focal necrotic areas in the viscera.(2) A bacteremia was found in cortisone-treated animals.This baeteremia consisted of organisms generally regarded as normal inhabitants of the gastrointestinal tract.