Concepedia

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome

Leslie B. Gordon, Monica E. Kleinman, Ralph B. D’Agostino, Heather M. Shappell, Marie Gerhard‐Herman, Leslie Smoot, Catherine M. Gordon, Robert Cleveland, Ara Nazarian, Brian D. Snyder,

Circulation · 2016 · 154 citations · 30 references

DOIFull text

Open access

Abstract

URL: http://www.clinicaltrials.gov. Unique identifiers: NCT00879034 and NCT00916747.

References

30

Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study

GA Block, TE Hulbert-Shearon, Levin Nw et al. · American Journal of Kidney Diseases · 1998 · 2.3K citations

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

Maria Eriksson, W. Ted Brown, Leslie B. Gordon et al. · Nature · 2003 · 2.2K citations · Full text

, , +5

Lamin A Truncation in Hutchinson-Gilford Progeria

Annachiara De Sandre‐Giovannoli, Rafaëlle Bernard, Pierre Cau et al. · Science · 2003 · 1.4K citations

, , +8

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome

Robert D. Goldman, Dale K. Shumaker, Michael R. Erdos et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

Melissa A. Merideth, Leslie B. Gordon, Sarah Clauss et al. · New England Journal of Medicine · 2008 · 734 citations · Full text