Concepedia

Publication | Open Access

CTLA-4 Limits Anti-CD20–Mediated Tumor Regression

DOIFull Paper Access

40

Citations

40

References

2016

Year

Zhenhua Ren, Jingya Guo, Jing Liao, Yan Luan, Zhida Liu, Zhichen Sun, Xiaojuan Liu, Yong Liang, Hua Peng, Yang‐Xin Fu
Clinical Cancer Research

Abstract

The therapeutic function of anti-CD20 depends on tumor-specific CD8<sup>+</sup> T-cell responses initiated by anti-CD20 through macrophages and DCs. CTLA-4 blockade can synergize with anti-CD20 to overcome adaptive immune response-related resistance in advanced B-cell lymphoma. Clin Cancer Res; 23(1); 193-203. ©2016 AACR.

References

YearCitations

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