Effects of chronic<scp>l</scp>-theanine administration in patients with major depressive disorder: an open-label study

Abstract

Our study suggests that chronic (8-week) l-theanine administration is safe and has multiple beneficial effects on depressive symptoms, anxiety, sleep disturbance and cognitive impairments in patients with MDD. However, since this is an open-label study, placebo-controlled studies are required to consolidate the effects.