PubMed · 2006 · 10 citations · 12 references
MedicineEndocrinologyPediatricsHuman NutritionPediatric EndocrinologyPediatric EpidemiologyIodine DeficiencyIodine NutritionThyroid DisordersIodine Deficiency EpidemiologyIodine Deficiency GoiterIodine Deficiency Prevention
INTRODUCTION: The aim of the study was to evaluate of efficiency of iodine prophylaxis based on obligatory model of salt iodization. MATERIAL AND METHODS: The study included 1444 children from the rural and urban area, with the proportional sex and age (8-12 years) distribution--432 children in 1992 (before salt iodization), 558 children in 2000 and 454 children in 2005 (during salt iodization from 1996). RESULTS: The prevalence of goiter detected in children population in 1992 was 40% (recount by current criteria), in 2005 was reduced to 6% (p < 0.01). Parallel, median of urinary iodine concentration increased from 44 microg/l in 1992 to 107 microg/l (p < 0.01) in 2005. The increase of incidence of autoimmunological thyroid diseases is observed, especially chronic thyroiditis. CONCLUSIONS: The study proves high efficiency of iodine prophylaxis in Wielkopolska Region, but it is still the area with mild iodine deficiency.
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Trace Elements in Human and Animal Nutrition
E. J. UNDERWOOD · Soil Science · 1963 · 4.5K citations · Full text