Concepedia

The effect of chlorzoxazone on acute pain after spine surgery. A randomized, blinded trial

Rikke Vibeke Nielsen, Jonna Storm Fomsgaard, Hanna Siegel, Robertas Martusevicius, Ole Mathiesen, Jørgen B. Dahl

Acta Anaesthesiologica Scandinavica · 2016 · 17 citations · 11 references

DOI

Abstract

No analgesic effect of single-dose chlorzoxazone was demonstrated in patients with acute pain after spine surgery. Based on these findings, chlorzoxazone cannot be recommended for immediate treatment of acute pain after such procedures.

References

11

SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials

An‐Wen Chan, Jennifer Tetzlaff, Douglas G. Altman et al. · Annals of Internal Medicine · 2013 · 7.4K citations · Full text

, , +16

CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials

Kenneth F. Schulz, Douglas G. Altman, David Moher · Journal of Pharmacology and Pharmacotherapeutics · 2010 · 2.1K citations · Full text

, , +16

Pain Intensity on the First Day after Surgery

H. U. Gerbershagen, Sanjay Aduckathil, Albert J. M. van Wijck et al. · Anesthesiology · 2013 · 1.5K citations

PRACTICAL STATISTICS FOR MEDICAL RESEARCH

John Ludbrook · Australian and New Zealand Journal of Surgery · 1991 · 1.2K citations

, , +2

Minimum clinically important difference in lumbar spine surgery patients: a choice of methods using the Oswestry Disability Index, Medical Outcomes Study questionnaire Short Form 36, and Pain Scales

Anne G. Copay, Steven D. Glassman, Brian R. Subach et al. · The Spine Journal · 2008 · 1.2K citations

, , +11