Concepedia

The Role of Probiotics in Lipopolysaccharide-Induced Autophagy in Intestinal Epithelial Cells

Chaoqun Han, Zhen Ding, Huiying Shi, Wei Qian, Xiaohua Hou, Rong Lin

Cellular Physiology and Biochemistry · 2016 · 70 citations · 37 references

DOIFull text

Open access

Abstract

We provide evidence that autophagy mediation by probiotics may be involved in enteroprotection against LPS-induced intestinal epithelial toxicity, and could serve as a novel mechanism through which probiotics promote and maintain gut homeostasis.

References

37

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

John D. Rioux, Ramnik J. Xavier, Kent D. Taylor et al. · Nature Genetics · 2007 · 1.7K citations · Full text

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Bacteriocin production as a mechanism for the antiinfective activity of <i>Lactobacillus salivarius</i> UCC118

Sinéad C. Corr, Yin Li, Christian U. Riedel et al. · Proceedings of the National Academy of Sciences · 2007 · 832 citations · Full text

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Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

Chinmoy Sarkar, Zaorui Zhao, Stephanie Aungst et al. · Autophagy · 2014 · 340 citations · Full text

Effect of probiotics on pro-inflammatory cytokines and NF-κB activation in ulcerative colitis

Sahar K. Hegazy · World Journal of Gastroenterology · 2010 · 275 citations · Full text

Strengthening of the intestinal epithelial tight junction by <i>Bifidobacterium bifidum</i>

Chen-Yu Hsieh, Toshifumi Osaka, Eri Moriyama et al. · Physiological Reports · 2015 · 235 citations · Full text