Inflammatory Mediators and Intestinal Injury

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

Life Sciences, Cell Biology, Physiology +9

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Kevin J. Tracey, Bruce Beutler, Stephen F. Lowry et al. · Science · 1986 · 2.6K citations

Veterinary Medicine, Immunology, Physiology +17

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

Stella Kourembanas, Philip A. Marsden, L. P. McQuillan et al. · Journal of Clinical Investigation · 1991 · 690 citations · Full text

Life Sciences, Cell Biology, Physiology +15

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).

Merle L. Blank, TEN‐CHING LEE, Veronica Fitzgerald et al. · Journal of Biological Chemistry · 1981 · 438 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

S M Prescott, Guy A. Zimmerman, Thomas M. McIntyre · Proceedings of the National Academy of Sciences · 1984 · 436 citations · Full text

Medicine, Biochemistry, Cell Biology +17