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Assessment of cognitive function in elderly patients treated with naproxen. A prospective study.
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1989
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NeuropsychologyAgingElderly PatientsCognitive TestsAlzheimer's DiseaseNeurologyProspective StudyAging-associated DiseaseHealth SciencesPsychiatryGeriatricsVascular DementiaRehabilitationCognitive FunctionCognitive PerformanceCognitive FunctionsVascular Cognitive DisorderCognitive DysfunctionDementiaNeuroscienceGeriatric AssessmentMedicine
Cognitive functions were assessed in 12 elderly patients prior to and following a three-week therapeutic course of Naproxen, 750 mg/day. Four of the patients deteriorated in one of the four cognitive tests, one of these patients in two tests. However, none of these changes reached statistical significance. Although non-steroidal anti-inflammatory drugs can cause some cognitive alteration in the elderly, this change is mild, and its clinical meaning questioned.