Further observations on the effects of large doses of irradiated ergosterol

Abstract

RECENT observations on the effects produced in animals by excessive feeding with irradiated ergosterol have provided definite results which are at variance. Pfannensteil [1927], On the other hand, They found that rats failed to gain in weight when fed with similar amounts of irradiated ergosterol, and when killed, after being fed in this way for ab6ut 40 days, showed calcium phosphate calculi in the urinary tract. Dixon and Hoyle.used ergosterol which had been irradiated in oily solution, and they suggested that the medium in which irradiation is effected may be a deciding factor in determiTniTng the toxicity of the product as shown