Dynamics of Hole Trapping by G, GG, and GGG in DNA

Abstract

Hole transfer from an excited, DNA-intercalated injector (1), to either G or to the “traps” GG or GGG occurs with similar rates, and always results in oxidation of the proximate guanine residue. These results indicate that charge trapping in GG or GGG must occur by a relaxation mechanism (structural and/or energetic) which is inherent in these sequences in DNA duplexes.