Some Observations on the T, Tn and Sd^a Antigens and the Antibodies that Define Them

Abstract

T‐ and Tn‐activation are known to result in polyagglutinability of red blood cells. Unlike polyagglutinability associated with the presence of the Cad antigen, there is no association in these two states with the antigen Sda. Alteration or destruction of the T‐receptor on T‐activated cells by the proteases fidn and papain is strictly dependent on the strength of the protease solution used. There is no correlation of amounts of anti‐T and anti‐Tn in normal sera.