Studies on neplanocin a, new antitumor antibiotic. I. Producing organism, isolation and characterization.

Satoshi Yaginuma, Naoki Muto, Masatoshi Tsujino, +3

The Journal of Antibiotics

Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.

R. T. BORCHARDT, B T Keller, Usha Patel-Thombre

Journal of Biological Chemistry

Molecular BiologyMouse L929 CellsAntiviral DrugNeplanocin ACulture Medium +15

Neplanocin A. A cyclopentenyl analog of adenosine with specificity for inhibiting RNA methylation.

Robert I. Glazer, M C Knode

Journal of Biological Chemistry

Cyclopentenyluridine and cyclopentenylcytidine analogs as inhibitors of uridine-cytidine kinase

Mu Ill Lim, James D. Moyer, Richard L. Cysyk, +1

Journal of Medicinal Chemistry

Preclinical TherapeuticsAltmetric Attention ScorePharmacotherapySystem PharmacologyPre-clinical Pharmacology +16

Total synthesis of (−)-neplanocin A

Mu‐Ill Lim, Víctor E. Márquez

Tetrahedron Letters

Bioorganic ChemistryTotal SynthesisPharmacologySynthetic ChemistryNatural Product Synthesis

Patterns of cell survival following treatment with antitumor agents in vitro

Benjamin Drewinko, Pamela Roper, Barthel Barlogie

European Journal of Cancer (1965)

Tumor BiologyOncologyTumor MicroenvironmentAntitumor AgentsMedicine +9

Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses

William M. Shannon, G. Arnett, Louise Westbrook, +3

Antimicrobial Agents and Chemotherapy

Related Carbocyclic AnalogsAntiviral ActivityMedicineImmunologyHong Kong +9

A synthetic approach towards neplanocin A: Preparation of the optically active cyclopentene moiety from D-ribose

Mu‐Ill Lim, Víctor E. Márquez

Tetrahedron Letters

Synthetic Approach TowardsBioorganic ChemistryHeterocyclicActive Cyclopentene MoietyBiochemistry +6

Effects of human immune interferon on cell viability, (2',5')oligoadenylate synthesis, and polyamine-dependent protein phosphorylation in human colon carcinoma cells in vitro.

Mrunal S. Chapekar, Robert I. Glazer

PubMed

Chemoprevention StrategyImmunologyPathologyImmunologic MechanismImmune System +18

The carbocyclic analog of cytidine, synthesis and antineoplastic activity

Y. Fulmer Shealy, C. Allen O’Dell

Journal of Heterocyclic Chemistry

Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceHeterocyclicIntermediate Stages +13