Pig‐to‐nonhuman primate solid organ xenografting: recent achievements on the road to first‐in‐man explorations

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

Muhammad M. Mohiuddin, Avneesh K. Singh, Philip C. Corcoran et al. · Nature Communications · 2016 · 469 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Pre‐transplant antibody screening and anti‐CD154 costimulation blockade promote long‐term xenograft survival in a pig‐to‐primate kidney transplant model

Laura Higginbotham, Dave Mathews, Cynthia A. Breeden et al. · Xenotransplantation · 2015 · 220 citations · Full text

Life Sciences, Immunology, Nephrology +17

Pig kidney graft survival in a baboon for 136 days: longest life‐supporting organ graft survival to date

Hayato Iwase, Hong Liu, Martin Wijkstrom et al. · Xenotransplantation · 2015 · 209 citations · Full text

Medicine, Immunology, Surgery +14

B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months

Muhammad M. Mohiuddin, Philip C. Corcoran, Avneesh K. Singh et al. · American Journal of Transplantation · 2011 · 158 citations · Full text

Life Sciences, Immunology, Surgery +17

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation

Muhammad M. Mohiuddin, Avneesh K. Singh, Philip C. Corcoran et al. · Journal of Thoracic and Cardiovascular Surgery · 2014 · 132 citations · Full text

Life Sciences, Cardiology, Immunology +12