MedicineBiochemistryNephrologyClinical BiochemistryDialysisHemodialysisHeavy Metal AnalysisRenal DiseaseElution Profile AnalysisFlame Atomic Absorption SpectrometrySerum Protein Binding
The binding of aluminum in the serum of a normal male volunteer was examined using gel filtration chromatography and flameless atomic absorption spectrometry. The elution profile obtained with Sephacryl S-200 gel separated the aluminum into four major peaks. These peaks appear to be associated with a high molecular weight protein(s), albumin, and possibly some low molecular weight protein(s) and/or some inorganic anions. The elution profile for a renal dialysis patient gave similar results.