Concepedia

Apparent "down-regulation" of human platelet alpha 2-adrenergic receptors is due to retained agonist.

Joel S. Karliner, Harvey Motulsky, P A Insel

Molecular Pharmacology · 1982 · 63 citations · 0 references

Concepts

MedicinePharmacologyPhysiologyCell SignalingPharmacodynamicsSignal TransductionPlatelet ActivationPlatelet AggregationPlatelet FunctionPlatelet PhysiologyReceptor DesensitizationReceptor RegulationAdrenergic Receptor AgonistsAgonist ActivityAlpha-2 AgonistsAlpha-adrenergic AgonistsDesensitization In Adrenergic ReceptorsPlatelet DesensitizationPlatelet Responses To Agonists