Expression of molecular messages for angiogenesis by fibroblasts from aneurysmal abdominal aorta versus dermal fibroblasts.

Abstract

VEGF and TNF were upregulated, as expected. However, the upregulation of monocyte chemotactic and activating factor (MCAF) and monocyte-derived neutrophil chemotactic factor (MDNCF) suggest that the fibroblast may be more significantly involved in driving the inflammatory response that leads to AAA than previously realized.