Concepedia

Designing piperlongumine-directed anticancer agents by an electrophilicity-based prooxidant strategy: A mechanistic investigation

Wenjing Yan, Qi Wang, Cui‐Hong Yuan, Fu Wang, Yuan Ji, Fang Dai, Xiaoling Jin, Bo Zhou

Free Radical Biology and Medicine · 2016 · 55 citations · 49 references

DOI

Concepts

References

49

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Masao Saitoh · The EMBO Journal · 1998 · 2.4K citations · Full text

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Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie et al. · Science · 1997 · 2.3K citations

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The antioxidant function of the p53 tumor suppressor

Anna Sablina, Andrei V. Budanov, G. V. Ilyinskaya et al. · Nature Medicine · 2005 · 1.1K citations · Full text

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

Atan Gross, Jennifer Jockel, Michael C. Wei et al. · The EMBO Journal · 1998 · 1.1K citations · Full text

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