Concepedia

Squamous Metaplasia Is Increased in the Bronchial Epithelium of Smokers with Chronic Obstructive Pulmonary Disease

Helen M. Rigden, Ahmad Solehin Alias, Thomas Havelock, Rory O’Donnell, Ratko Djukanović, Donna E. Davies, Susan J. Wilson

PLoS ONE · 2016 · 86 citations · 39 references

DOI Full text

Open access

Abstract

In subjects with COPD there is a loss of pseudostratified epithelium accompanied by an increase in squamous metaplasia with transition into a fully squamous epithelium and expression of early markers of carcinogenesis.

References

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