Coexistence of Th1/Th2 and Th17/Treg imbalances in patients with allergic asthma.

Yuheng Shi, Guochao Shi, Huanying Wan, Lihua Jiang, Xiangyan Ai, Haixing Zhu, Wei Tang, Jia-yun Ma, Xiaoyan Jin, Bo-ying Zhang

PubMed · 2011 · 137 citations · 0 references

Abstract

Imbalances in Th1/Th2 and Th17/Treg were found in patients with allergic asthma. Furthermore, elevated Th17 cell responses, the absence of Tregs and an imbalance in Th17/Treg levels were associated with moderate to severe asthma.