Langerhans' cell histiocytosis: complete remission after oral isotretinoin therapy.

Abstract

We report a 48-year-old male patient with Langerhans' cell histiocytosis, who showed a complete remission of his single-system skin disease after an 8-month therapy with oral isotretinoin (1.5 mg/kg/day) and remained free of recurrence and visceral involvement for 5 years