HDAC inhibitor-loaded bone cement for advanced local treatment of osteosarcoma and chondrosarcoma. - Concepedia

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HDAC inhibitor-loaded bone cement for advanced local treatment of osteosarcoma and chondrosarcoma.

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References

2014

Year

Marcus Tonak, Marc A. Becker, Claudine Graf, Lukas Eckhard, Matthias Theobald, Pol-Maria Rommens, D. Proschek

Abstract

A local cytotoxic therapy in the treatment of osteosarcoma and chondrosarcoma might improve the rate of metastasis and survival of patients. Our results present an encouraging approach to loading PMMA with anti-neoplastic drugs.