PubMed · 2012 · 22 citations · 0 references
Life SciencesGeneticsImmunologyImmunogeneticsImmunology Of Infectious DiseasesInnate ImmunityHla TypingHuman Leukocyte Antigen SystemKiller Cell Immunoglobulin-like Receptor GeneticsMajor Histocompatibility ComplexNatural Killer Cell BiologyNatural Killer Cell RegulationHla AllelesHla Class I MoleculesInnate Immunity PathwaysKiller Cell Immunoglobulin-like Receptor Gene FamilyKiller Cell Immunoglobulin-like Receptor Gene PolymorphismKiller Cell Immunoglobulin-like Receptor GenotypingKiller Cell Immunoglobulin-like Receptor-human Leukocyte Antigen InteractionsKiller-cell Immunoglobulin-like Receptors
These findings imply a genetic imbalance between activating and inhibitory KIR genes and KIR-HLA combinations in Lur TB patients. Low level of activating KIR3DS1 and its combination with HLA-B Bw4Ile80 ligand might have an influence on the susceptibility to TB in Lur population of Iran.