[Chemical constituents from marine fungus Penicillium thomii].

Abstract

AIM: To investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach. METHODS: The constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis. RESULTS: Five compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii. CONCLUSION: Penicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.