A novel method to promote behavioral improvement and enhance mitochondrial function following an embolic stroke

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine · 2008 · 6.6K citations · Full text

Medicine, Neurology, Neurocritical Care +11

Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

Werner Hacke, Markku Kaste, Cesare Fieschi et al. · The Lancet · 1998 · 3.7K citations

Medicine, Neurology, Pharmacotherapy +12

Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

Werner Hacke, Geoffrey A. Donnan, Cesare Fieschi et al. · The Lancet · 2004 · 2.6K citations

Medicine, Neurology, Meta-analysis +6

Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.

Patrick D. Lyden, Thomas Brott, Barbara C. Tilley et al. · Stroke · 1994 · 1.3K citations · Full text

Life Sciences, Neurology, Rehabilitation Medicine +17

A call for transparent reporting to optimize the predictive value of preclinical research

Story C. Landis, Susan Amara, Khusru Asadullah et al. · Nature · 2012 · 1.2K citations · Full text

Public Health, Biostatistics, Evidence-based Practice +16