Pioglitazone, a Peroxisome Proliferator-Activated Receptor γ Agonist, Ameliorates Chronic Kidney Disease by Enhancing Antioxidative Capacity and Attenuating Angiogenesis in the Kidney of a 5/6 Nephrectomized Rat Model - Concepedia

Concepedia

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Pioglitazone, a Peroxisome Proliferator-Activated Receptor γ Agonist, Ameliorates Chronic Kidney Disease by Enhancing Antioxidative Capacity and Attenuating Angiogenesis in the Kidney of a 5/6 Nephrectomized Rat Model

DOI Full Paper Access

26

Citations

26

References

2016

Year

Li Sun, Quan Yuan, Tianhua Xu, Yao Li, Feng Jiang-min, Jianfei Ma, Lining Wang, Changlong Lu, Danan Wang

Cellular Physiology and Biochemistry

Abstract

The current study demonstrates that pioglitazone benefits renal failure through activation of the antioxidative system and inhibition of angiogenesis in the injured kidney. Our study provides preliminary evidences for the potential application of this agent in the treatment of CKDs.

References

	Year	Citations

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