Post-transcriptional gene silencing activity of human GIGYF2

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

Isabelle Behm‐Ansmant, Jan Rehwinkel, Tobias Doerks et al. · Genes & Development · 2006 · 1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

Ramesh S. Pillai, Caroline G. Artus, Witold Filipowicz · RNA · 2004 · 390 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

Hansruedi Mathys, J. Basquin, Sevim Ozgur et al. · Molecular Cell · 2014 · 321 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

A DDX6-CNOT1 Complex and W-Binding Pockets in CNOT9 Reveal Direct Links between miRNA Target Recognition and Silencing

Ying Chen, Andreas Boland, Duygu Kuzuoğlu‐Öztürk et al. · Molecular Cell · 2014 · 297 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

Dinghai Zheng, Nader Ezzeddine, Chyi-Ying A. Chen et al. · The Journal of Cell Biology · 2008 · 229 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17