Synthesis of Acyl Terphenyls and Higher Polyaromatics via Base-Promoted C–H Functionalization of Acetylarenes with Arylacetylenes

Abstract

KO(t)Bu/DMSO-promoted C-H functionalization of acetylarenes with arylacetylenes (100 °C, 30 min), generating β,γ-ethylenic ketones, triggers upon further heating (100 °C, 4 h, with or without acidifying additive) the cascade assembly of acyl terphenyls and higher polyaromatics in good yields.