Bizarre Deformities in Offspring of User of Lysergic Acid Diethylamide

Abstract

An infant with a rare combination of severe congenital deformities was born to a woman with a history of using lysergic acid diethylamide. Previously described patients bearing a similarity to this infant were of Puerto Rican parents, most of consanguineous marriage, and in none of these cases was use of this drug indicated. The current state of knowledge of the effects of the compound is such that no definite inference can be made about the current case. All reported cases similar to this one appear to have been due to an unusual recessive mode of inheritance or chromosomal aberration.